GLP-1 Weight Loss
AOD-9604
A modified fragment of human growth hormone engineered specifically for fat metabolism — without the growth-promoting effects or side effects of full HGH. Physician-prescribed and pharmacy-compounded for California patients.
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Physician-reviewed peptide therapy, prescribed only when appropriate.
Protocol at a glance
- Dose
- 300 mcg
- Route
- Subcutaneous injection
- Frequency
- Daily
- Timing
- Morning, fasted
- Course
- 8–16 weeks to assess
- Typical cost
- $100–200/mo
Physician-reviewed. Prescribed only if appropriate after a telehealth consult — full refund if a licensed clinician determines it isn't right for you.
Why patients choose it
Why patients choose AOD-9604
Targeted fat metabolism
Stimulates lipolysis and inhibits lipogenesis through an HGH-like pathway, without the appetite suppression mechanism of GLP-1s.
Clean safety profile
Doesn't raise IGF-1, cause insulin resistance, or carry the musculoskeletal side effects of full HGH therapy.
Built for recomposition
Helps reduce body fat while preserving lean mass — a fit for patients already at a reasonable weight chasing stubborn fat.
Overview
What AOD-9604 is
AOD-9604 (Anti-Obesity Drug 9604) is a synthetic peptide fragment derived from the C-terminal end of human growth hormone (amino acids 176–191). It was developed by Monash University in Australia specifically to isolate HGH's fat-burning properties while eliminating its growth-promoting effects.
The result is a peptide that stimulates lipolysis and inhibits lipogenesis through an HGH-like mechanism, but without raising IGF-1, increasing blood sugar, or causing the long-term complications associated with full growth hormone therapy.
Candidacy
Who it's for
California patients who ask about AOD-9604 typically fall into one of these groups:
- Patients who want fat loss without the appetite suppression mechanism of GLP-1s
- Those who've experienced significant GI side effects from semaglutide and need an alternative
- Body recomposition goals — reducing fat while preserving or building lean mass
- Patients on GH secretagogue protocols who want to add targeted fat metabolism
- Individuals with stubborn body fat deposits not responding to diet and exercise alone
What to expect
How it unfolds, week by week
01
Weeks 1–4
Daily fasted-morning dosing establishes a routine. AOD-9604 has a short half-life (~30 minutes) and mobilizes fat quickly after injection, though visible change is minimal this early.
02
Weeks 8–16
Most patients notice changes in body composition and fat distribution in this window with consistent daily use paired with a calorie-appropriate diet and regular exercise.
03
Beyond 16 weeks
Results continue to build with adherence. Because the peptide facilitates fat mobilization, lifestyle factors determine whether that fat is oxidized for energy or re-deposited.
AOD-9604 vs. Semaglutide
| AOD-9604 | Semaglutide | |
|---|---|---|
| Mechanism | Targeted fat metabolism — stimulates lipolysis and inhibits lipogenesis via an HGH-like pathway. | GLP-1 receptor agonist — appetite suppression and broader metabolic effects. |
| Weight effect | Body recomposition — reduces fat percentage while preserving lean mass. | Larger absolute weight loss through appetite suppression. |
| Side effects | Mild injection site reactions; no appetite suppression or GI effects. | GI side effects are common, particularly when titrating up. |
| Best for | Patients already at a reasonable weight reducing stubborn body fat. | Patients with significant weight to lose. |
Safety
Side effects & contraindications
AOD-9604 has an excellent safety profile. In clinical trials conducted for an FDA IND application, no significant adverse effects were observed. It does not raise IGF-1, does not cause insulin resistance, and does not have the musculoskeletal side effects associated with full HGH therapy.
Mild injection site reactions are the most commonly reported issue. As with any prescription therapy, disclose your full medical history to your prescribing physician before starting.
Pricing
Cost in California
Compounded AOD-9604 runs $100–200/month — lower than most other peptide protocols due to simpler compounding and lower dose volume. See our full cost guide.
FAQ
AOD-9604 questions
Related peptides
Often explored together
Semaglutide
GLP-1 agonist for significant appetite-driven weight loss.
Learn more →Tirzepatide
Dual GIP/GLP-1 agonist for stronger weight reduction.
Learn more →Tesamorelin
GHRH analogue studied for visceral fat reduction.
Learn more →MOTS-c
Mitochondrial peptide tied to metabolism and fat utilization.
Learn more →Get AOD-9604 in California
Physician consultation, prescription, and pharmacy delivery. No clinic visit required.
Check Your EligibilityAOD-9604
Physician-reviewed